Granulomatosis disciformis in a non-diabetic patient*

ciated with diabetes mellitus, with only LN associated to this condition. However, this theory was proven to be unfounded, as it was discovered that both diseases can be associated or not with diabetes mellitus.1,2,3 In the present case, a 46-year-old female patient reported the appearance of annular lesions on her forearms and legs over the past three years, with local yet discreet pruritis. The patient presented systemic arterial hypertension, which was treated with propranolol, and the patient denied any prior diagnosis of diabetes mellitus. Upon physical examination, it was possible to observe annular erythematous plaques, with infiltrated edges, together with an atrophic and telangiectatic center, with a yellowish color and an aspect of cigarette paper when wrinkled (Figures 1 and 2). The initial hypothetical diagnosis was of LN, and a biopsy of a lesion on the right forearm was, therefore, performed. The anatomopathologic exam showed a perivascular and interstitial inflammatory infiltrate, comprised of lymphocytes, plasmocytes, and epithelioid macrophages, with the presence of Langhans multinucleated giant cells and thick collagen fibers (Figure 3). The biopsy proved to be compatible with the diagnosis of GDML. Laboratory exams were also requested to investigate the lipid profile and the change in the glycemic curve, which presented no changes. The patient began her treatment with sulfone, administered orally, and topical clobetasol presenting, to date, partial regression of the lesions.